Which tests are typically performed to check for the presence of lupus anticoagulant?

The presence of lupus anticoagulant is typically assessed through specialized coagulation tests. These tests are specifically designed to evaluate the coagulation system's response to anticoagulants, and they help identify the presence of specific inhibitors that can interfere with the coagulation pathways. Lupus anticoagulant, which is an antibody associated with antiphospholipid syndrome, leads to a prolonged activated partial thromboplastin time (aPTT) in vitro, and specialized tests such as the dilute Russell viper venom time (dRVVT) and mixing studies are used to confirm its presence.

Other tests listed, such as a comprehensive metabolic panel, complete blood count, and liver function tests, do not specifically assess for lupus anticoagulant. Instead, they evaluate different aspects of bodily function and health, such as metabolic status, blood cell counts, and liver health, which do not provide the necessary information related to coagulation disturbances caused by lupus anticoagulant.