What does the platelet aggregation test measure?

The platelet aggregation test assesses the ability of platelets to clump together, which is a crucial function for normal hemostasis. When a blood vessel is injured, platelets are activated and begin to aggregate at the site of injury, forming a temporary plug that helps prevent excessive bleeding. This test can provide valuable information about the functionality and activity of platelets, which is important for diagnosing various bleeding disorders or conditions that affect clotting.

By evaluating how well platelets aggregate in response to specific agonists (substances that can promote aggregation), healthcare professionals can gain insights into the underlying mechanisms of platelet function. Conditions such as von Willebrand disease, certain platelet function disorders, and the effects of antiplatelet medications can all influence aggregation responses, making this test a vital tool in hematology.